This one is also on (deader than Christina Applegate's acting career) deviantART for those so inclined.
Original Sketch by Tooner
Colors by Phillipthe2
Aside from the green skin and that whole telekinesis thing, Shego could be Peggy Bundy's doppelganger.
...and my gawd, I just notice how huge Katey Sagal's ankles are. :D